RISE for Discovery

The RISE registry is the first and largest Electronic Health Record (EHR) enabled rheumatology registry in the United States. RISE data represents the clinical experience of more than 1,000 rheumatology care providers, with a unique prevalence of community-based rheumatology practices and clinicians.

RISE captures comprehensive, real world data at the point of care, directly from the EHR systems of participating practices, providing unique insights into the management of all rheumatic diseases, including rare and unique disease. Unlike datasets based on insurance or pharmacy claims, RISE offers comprehensive, yet highly granular rheumatology-specific clinical insights, including diagnoses, medications, labs, and disease activity measures.

RISE is not dependent on a case report form; instead, it automatically extracts data on the entire population of patients at participating practices. This innovative registry includes patients with all medical conditions seen by a rheumatologist and all insurance types. RISE patient data include patient demographics, such as age, sex, and geography, and clinical characteristics, such as diagnoses, medications, and outcomes.

Although osteoarthritis and rheumatoid arthritis are the most common diagnoses, the registry includes all diseases seen by rheumatologists, such as psoriatic arthritis or systemic lupus erythematosus, and includes patients with many rare diseases, including granulomatosis with polyangiitis, microscopic polyangiitis, Behçet's syndrome, Takayasu's arteritis, inflammatory myopathies, and more.

Since RISE patient data comes directly from EHRs, it provides a robust source of patient information. These data are more up to date than data from administrative claims or chart reviews, which often have significant delays in aggregating results.